Clinical application of impression cytology

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Impression cytology in Down's syndrome.

AIM To evaluate both the number and the average distribution of goblet cells, which are responsible for the production of the mucin layer of the tear film, in the bulbar conjunctiva of patients with Down's syndrome. Previous research had used the ferning test to indicate an alteration in Down's syndrome, but had not determined which film layer was involved. METHODS The presence of goblet cell...

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Impression cytology of the ocular surface.

Impression cytology refers to the application of a cellulose acetate filter to the ocular surface to remove the superficial layers of the ocular surface epithelium. These cells can then be subjected to histological, immunohistological, or molecular analysis. Proper technique is essential as the number of cells sampled can vary considerably. Generally two to three layers of cells are removed in ...

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Role of impression cytology during hypovitaminosis A.

AIMS Evaluation of the morphological damage to the ocular surface of patients operated for biliopancreatic diversion for pathological obesity and the correlation of impression cytology with vitamin A plasma levels, adaptometry, and other general variables. METHODS 48 patients (15 males, 33 females, age range 21-73) and 34 normal subjects were examined with fluorescein and rose bengal, a plasm...

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Impression cytology of conjunctival melanosis and melanoma.

Impression cytology using cellulose acetate paper has been used in various ocular surface disorders as a simple non-invasive diagnostic test. To assess its value in differentiating melanocytic tumours, 24 patients with a range of pigmented lesions of the conjunctiva were examined using this technique. Cytological and histological diagnoses were compared in 23 cases. In 73% of cases impression c...

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Conjunctival impression cytology in computer users.

INTRODUCTION It is known that the computer users develop the features of dry eye. OBJECTIVE To study the cytological changes in the conjunctiva using conjunctival impression cytology in computer users and a control group. MATERIALS AND METHODS Fifteen eyes of computer users who had used computers for more than one year and ten eyes of an age-and-sex matched control group (those who had not ...

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ژورنال

عنوان ژورنال: Bulgarian Review of Ophthalmology

سال: 2019

ISSN: 1311-0624

DOI: 10.14748/bro.v63i2.6044